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Lyme Disease Treatment and Prognosis
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Antibiotics
Most cases of Lyme disease can be cured with a few weeks of antibiotics taken by mouth. Antibiotics commonly used for oral treatment include doxycycline, amoxicillin, or cefuroxime axetil. Patients with certain neurological or cardiac forms of illness may require intravenous treatment with drugs such as ceftriaxone or penicillin. The table below summarizes current treatment recommendations as developed by the Infectious Disease Society of America (IDSA) in consultation with Lyme disease experts and CDC.
Pregnancy
Studies of women infected during pregnancy have found that there are no negative effects on the fetus if the mother receives appropriate antibiotic treatment for her Lyme disease. In general, treatment for pregnant women is similar to that for non-pregnant persons, although certain antibiotics are not used because they may affect the fetus. If in doubt, discuss treatment options with your health care provider.
Length of Treatment
Patients treated with antibiotics in the early stages of the infection usually recover rapidly and completely. A few patients, particularly those who are first diagnosed with later stages of the disease, may have persistent or recurrent symptoms. These patients may benefit from a second 4-week course of therapy. Longer courses of antibiotic treatment have not been shown to be beneficial and have been linked to serious complications, including death. For details on long term treatment trials sponsored by the National Institutes of Health (NIH) visit the NIH Lyme Disease web site.
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